This is unpublished
| Mentor | Affiliation | Field of Study |
|---|---|---|
| Kristina Adams Waldorf, M.D. (R38 PI and Program Director) |
UW Prof. of OB/GYN, Adj. Prof. of Global Health, Washington National Primate Research Center Core Scientist, UW Center for Immunity and Immunotherapies, Center for Emerging and Reemerging Infectious Diseases, Center for Reproductive Sciences | Investigates the pathogenesis of bacterial and viral infections in pregnancy (SARS-CoV-2, influenza A, Zika virus, Group B Streptococcus), maternal-placental-fetal innate immunity, therapeutics to prevent preterm birth, nonhuman primate models of pregnancy. Clinical and translational scientist. |
| Mridu Acharya, Ph.D. | UW Assistant Prof. of Pediatrics, Seattle Children’s Research Institute, Center for Immunity and Immunotherapies | Regulation of B cell antigen receptor and toll-like receptor signaling and intracellular trafficking by integrins and related molecules, antiviral responses on systemic autoimmunity. |
| Daniel Blanco-Melo, Ph.D. |
Fred Hutchinson Cancer Center Assistant Prof., Vaccine and Infectious Disease Division |
Studies the biological mechanisms to combat viral infections; explores how changes in our antiviral strategies are driven by the constant struggle with past and current viral infections. |
| Marie Bleakley, M.D., Ph.D. | UW Assoc. Prof. of Medicine, Fred Hutchinson Cancer Center Assoc. Member of the Clinical Research Division | Studies T cell immunotherapy and graft engineering for hematologic disorders and pediatric cancers, clinical trials to evaluate the depletion of naïve T cells from peripheral blood stem cell grafts. Clinical and translational scientist. |
| Jane Buckner, M.D. | Benaroya Research Institute President and Member of Center for Translational Immunology | Studies the regulatory and effector immune mechanisms and their control in autoimmunity (Type 1 diabetes, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus and relapsing polychondritis). Clinical and translational scientist. |
| Helen Chu, M.D. | UW Prof. of Medicine | Clinical-translational research on (1) vaccines, antivirals, and diagnostics for respiratory viruses (2) immune correlates of protection against respiratory viruses and (3) maternal-fetal immunity against respiratory viruses. Clinical scientist. |
| Rhea Coler, Ph.D. | UW Prof. of Pediatrics, Seattle Children’s Research Institute | Pathogenesis of infectious disease, vaccine development of early and later preclinical stage candidates; leads a Vaccine Treatment Evaluation Unit laboratory site for evaluating candidate tuberculosis, COVID-19, and schistosomiasis vaccines. Clinical and translational scientist. |
| Jason Debley, M.D. | UW Prof. of Pediatrics, Seattle Children’s Research Institute, Center for Immunity and Immunotherapies | Innate immune responses of airway epithelial cells to respiratory viruses and how aberrant epithelial regulation of airway remodeling impacts asthma pathobiology. Clinical/translational scientist. |
| Cynthia Derdeyn, Ph.D. | UW Prof. of Lab Medicine and Pathology, Washington National Primate Research Center Core Scientist | HIV-1 and SIV transmission, pathogenesis, neutralizing antibody responses, immune escape, and pre-clinical vaccine development, vaccine-elicited antibody-mediated protection in nonhuman primates. Translational scientist. |
| Mary (Nora) Disis, M.D. | UW Prof. of Medicine, Dir. of the UW Institute for Translational Health Sciences | Antigen specific vaccines for the prevention of common solid tumor and solid tumor relapse. She currently has 4 vaccines against antigens in breast, ovarian, lung cancer in randomized Phase II clinical trials. Clinical/translational scientist. |
| Alison Drake, Ph.D. | UW Associate Prof. of Global Health | HIV prevention among women and adolescents, incident maternal HIV infections, vertical HIV transmission, adolescent reproductive health, mobile health, and family planning. Clinical scientist. |
| David Fredricks, Ph.D. | UW Prof. of Medicine and Microbiology, Fred Hutchinson Cancer Center Member | Studies human microbial communities using both cultivation-independent molecular methods and in vitro cultivation approaches. Clinical scientist. |
| Lisa Frenkel, M.D. | UW Prof. of Pediatrics, Adj. Professor of Lab Medicine and Pathology, Seattle Children’s Research Institute | Investigates mechanisms underlying HIV persistence despite effective anti-viral therapy (ART). She is also a member of the NIH Pediatric AIDS Clinical Trials Group (PACTG) and the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT). Clinical scientist. |
| Deborah Fuller, Ph.D. | UW Prof. of Microbiology, Washington National Primate Research Center | >30 years of experience developing vaccines with a focus on DNA and RNA vaccines including immunogen design and technologies to optimize in vivo immunogenicity. NHP models of infectious diseases are central to her program including AIDS, HBV, etc. Clinical and translational scientist. |
| Denise Galloway, Ph.D. | UW Prof. of Microbiology, Fred Hutchinson Cancer Center Dir. of Pathogen Associated Malignancies | Studies small DNA tumor viruses [human papillomaviruses (HPVs) and human polyomaviruses; among the first groups to develop virus-like particles to study the natural history of HPV infections and identify immunoreactive epitopes. Clinical and translational scientist. |
| Jessica A. Hamerman, Ph.D. | Benaroya Research Institute Member, UW Affiliate Prof. of Immunology | Studies regulation of myeloid cells during homeostasis, infection, and autoimmunity; trafficking of monocytes and dendritic cells, and myeloid development. |
| Whitney Harrington, M.D., Ph.D. | UW Assistant Prof. of Pediatrics, Seattle Children’s Research Institute | Studies how intergenerational immune interactions impact susceptibility to infection during pregnancy and infancy, roles for maternal cells acquired by the offspring (maternal microchimerism) in fetal and infant immune development/early vaccine responses. Clinical scientist. |
| Stephen E. Hawes, Ph.D. | UW Prof. of Epidemiology | Cervical cancer and other HPV-associated cancers in high-risk populations including individuals with HIV infection; assessment of maternal/child outcomes related to conditions during pregnancy. Clinical scientist and epidemiologist. |
| Florian Hladik, M.D., Ph.D. | UW Prof. of OB/GYN, Research Division Chief of OB/GYN, Center for Reproductive Sciences | Mucosal transmission pathways of HIV, genetic variation triggering immune activation and HIV acquisition; Immunology Core Co-PI for the Microbicide Trials Network (MTN); co-directs the Immunology, Retrovirology and HIV Cure Core for the Seattle Center for AIDS Research (CFAR). Clinical and translational scientist. |
| Shaun Jackson, M.D., Ph.D. R38 Assistant Program Director |
UW Assoc. Prof. of Pediatrics, Adj. Professor of Lab Medicine and Pathology, Seattle Children’s Research Institute, Center for Immunity and Immunotherapies |
Studies mechanisms contributing to breaks in immune tolerance during the pathogenesis of humoral autoimmunity, immunopathogenesis of genetic immune dysregulation syndromes, spatial transcriptomics to understand human lupus nephritis, developing novel B cell-directed treatments for SLE. Clinical and translational scientist. |
| Heather Jaspan, M.D., Ph.D. | UW Assoc. Prof. of Pediatrics, Seattle Children’s Research Institute | Impact of HIV and other sexually transmitted infections (STI) on maternal and perinatal health, immunity in HIV-exposed infants; roles for the vaginal microbiome on immunity and reproductive health outcomes; optimization of pediatric HIV treatment in South Africa. Clinical scientist. |
| Grace C. John-Stewart, M.D., Ph.D. | UW Prof. of Global Health/Epidemiology/ Medicine/Pediatrics, Global WACh, Center for AIDS Research |
Infectious diseases research in women, adolescents, and children, as part of collaborative research in Kenya; clinical trials, molecular epidemiology, implementation science, and large-scale evaluations. Clinical scientist. |
| Meghan Koch, Ph.D. | Fred Hutchinson Cancer Center Assistant Member, Basic Sciences Div., UW Affiliate Assistant Prof. of Immunology | How maternal-offspring interactions influence neonatal health; immunity, metabolism, and the microbiota; maternal antibody development and function; interactions of antibodies with the host and resident gut microbiota and how perturbations in this process translate to long-term health outcomes. |
| Sylvia LaCourse, M.D. | UW Associate Prof. of Global Health/Medicine | Improving TB screening and prevention in HIV-infected peripartum women. Recent work has focused on novel non-sputum based TB diagnostics and the effect of pregnancy on LTBI screening and prevention approaches. Clinical scientist. |
| Jairam Lingappa, M.D., Ph.D. | UW Prof. of Global Health/Medicine | Pathogenesis of HIV-1 sexual transmission; identification of host biological correlates for risk of HIV-1 infection; HIV-1 prevention clinical trials and observational studies in African heterosexual HIV-1 serodifferent couples. Clinical scientist. |
| Peter Linsley, Ph.D. | Benaroya Research Institute Member, Center Director of Systems Immunology |
Systems approaches to elucidating mechanisms in treatment of autoimmune diseases; whole blood transcriptome profiling of Type 1 Diabetes; single cell RNA-Seq to characterize clonotypes and transcriptomes of antigen presenting cells. |
| Mignon Loh, M.D. | UW Prof. of Pediatrics and Dir. of Ben Towne Center for Childhood Cancer, Seattle Children’s Research Institute. | Studies immuno-oncology and the efficacy of immunotherapeutics for pediatric hematologic malignancies; Chair of the Children’s Oncology Group (COG) acute lymphoblastic leukemia (ALL) committee and is responsible for supervising and implementing national ALL trials at more than 210 COG institutions. Clinical scientist. |
| Jennifer Lund, Ph.D. | UW Prof. of Global Health, Fred Hutchinson Cancer Center Member | Antiviral and mucosal immunity; defining the role of tissue-resident memory T cells and regulatory T cells during mucosal virus infection; identifying novel mucosal immune correlates of protection from HIV-1 infection. |
| Sean Murphy, M.D., Ph.D. | UW Assoc. Prof. of Lab Medicine, Washington National Primate Research Center Core Scientist, Center for Emerging and Reemerging Infectious Diseases member | Investigates parasitic diseases, especially infections caused by malaria parasites; pre-clinical and clinical development of malaria vaccines; Seattle-based Malaria Clinical Trials Center. Clinical and translational scientist. |
| Evan Newell, Ph.D. | Fred Hutchinson Cancer Center Associate Member of the Vaccine and Infectious Disease Division | Characterizes antigen specific T cells in the context of human disease in terms of their biophysical and structural nature of T cell receptor–peptide-MHC interactions. |
| Marion Pepper, Ph.D. | UW Associate Professor and Chair of Immunology | Host response to various pathogens focusing on the isolation and characterization of small populations of polyclonal, antigen-specific cells; pathways that regulate lymphocyte differentiation/protection from disease during allergy/infection. |
| Martin Prlic, Ph.D. | Fred Hutchinson Cancer Center Assoc. Member of Vaccine and Infectious Disease Division | Defines cues that guide activation, differentiation, and maintenance of immune cell populations to learn how these cues could be manipulated for therapeutic purposes; placental immune cell populations including innate lymphoid cells. Clinical and translational scientist. |
| Lakshmi Rajagopal, Ph.D. | UW Prof. of Pediatrics and Global Health, Seattle Children’s Research Institute | Group B Streptococcus pathogenesis, host pathogen interactions, mouse, nonhuman primate models of pregnancy. |
| David Rawlings, M.D. | UW Prof. of Pediatrics, Adj. Prof. of Immunology, Dir. of Center for Immunity and Immunotherapies, Seattle Children’s Research Institute |
Lymphoid development and signaling leading to immunodeficiency, autoimmunity and/or malignancies; develops gene therapy and gene editing therapy for immune diseases. Clinical and translational scientist. |
| Stanley Riddell, M.D. | Fred Hutchinson Cancer Center Member of Immunotherapy Integrated Research Center | Investigates contributions of distinct human T cell subsets to protective immunity to pathogens and tumors; clinical application of adoptive T cell therapy for viral diseases and cancer using unmodified and genetically modified antigen-specific T cells of defined compositions. |
| Noah Sather, Ph.D. | UW Assoc. Prof. of Pediatrics, Seattle Children’s Research Institute | Develops novel vaccine immunogens and vaccination strategies; deciphering the mechanisms of antibody mediated protective immunity by HIV or malaria vaccination. |
| Joshua Schiffer, M.D. | UW Assoc. Prof. of Medicine, Fred Hutchinson Cancer Center Member | Develops mechanistic mathematical models to capture dynamic interactions between viral pathogens and the immune system; mathematical modeling of tissue resident T-cell spatial activity, human microbiome dynamics, and HIV reservoir. |
| Chetan Seshadri, M.D. | UW Associate Prof. of Global Health/Medicine | Translational immunology, particularly related to vaccines for tuberculosis. Clinical and translational scientist. |
| Olusegun Soge, Ph.D. | UW Associate Prof. of Global Health and Medicine | Mechanisms of antimicrobial resistance (AMR) in a wide range of clinically important bacteria; domestic and international surveillance of N. gonorrhoeae AMR. Clinical scientist. |
| Bruce Torbett, Ph.D. | UW Prof. of Pediatrics and Assoc. Dir. of the Center for Immunity and Immunotherapies, Seattle Children’s Research Institute | Studies how HIV adapts to antivirals and generates inhibitor resistance yet maintains fitness; developed novel sequencing and computational methods to follow genotypic changes during HIV evolution to inhibitors. |
| Kevin Urdahl, MD, Ph.D. | UW Prof. of Pediatrics, Adj. Prof of Immunology, Seattle Children’s Research Institute |
Immunity against Mycobacterium tuberculosis infection; tuberculosis vaccines; microbial immunology, genetics, and vaccinology. Clinical and translational scientist. |
| Wesley Van Voorhis, M.D., Ph.D. | UW Prof. of Medicine, Dir. of Center for Emerging and Reemerging Infectious Diseases, Dir. of UWARN (United World Antiviral Research Network) | Develops target-based drugs employing iterative structure-based drug development; characterizing new preclinical drug candidates for treatment of cryptosporidiosis and toxoplasmosis. Clinical and translational scientist. |
| Lucia Vojtech, Ph.D. | UW Research Associate Prof. of OB/GYN | Investigates immunity in the genital tract; earliest stages of alloantigen specific immunity to the fetus and protective immune responses against Chlamydia trachomatis; immunity to paternal antigen exposure in the female genital tract. Clinical and translational scientist. |