The Adams Waldorf Lab is trying to find out how the virus that causes the infectious disease called COVID-19, might cause problems in pregnancy such as preterm labor and more severe disease in the mother. The purpose of this study is to investigate the mother’s and newborn’s immune response between women with COVID-19 in pregnancy, influenza-like illness and healthy pregnancies.
Who is eligible: Any pregnant woman older than 18 with suspected or confirmed COVID-19 or an influenza-like illness who speaks English and has the capacity to consent. Healthy pregnant women are also eligible.
Consent Forms (2):
Consent - English
HIPAA - English
Consent - Spanish
HIPAA - Spanish
A message from Dr. Kristina Adams Waldorf:
For many of us, this is an anxious time as we watch the daily unfolding public health crisis of COVID-19. We are working hard to find new therapies and to understand how the virus works. In mid-January, when I saw infections begin to pop up outside of the Wuhan, China region, I knew that we had to do something. When I say “something,” that means pivot my entire research program to begin researching this new virus and becoming part of the solution.
As a physician and scientist, some of the early reports didn’t make sense. Why were there no visible cases of children and pregnant women dying? Why are older men and women so vulnerable to this virus and what can we learn from how younger women, pregnant women and children fight this infection? My research partners and I quickly made a plan to work together – to study the virus in a laboratory with the strictest and highest level of biosafety containment in Washington State. This work is likely to uncover defects in the immune response of older men and women that are exploited by the virus – which will help us to target the right therapeutics to this vulnerable group.
In Seattle, we are at the epicenter of the outbreak. As an obstetrician, I quickly brought together research partners at 6 major hospital systems in Washington State to analyze the outcomes of pregnant women and newborns, who become infected over the next few months. Some reports are surfacing that lung disease in the pregnant mother is forcing obstetricians to deliver women prematurely. Can the virus cross the placenta? Are newborns affected by an exposure during pregnancy and will they require specialized follow-up? This research will likely guide public health policy for families in Washington State and other parts of the world.
To learn more about the Adams Waldorf Lab, visit this page.