In the News

The first case series from the Washington State COVID-19 in Pregnancy Collaborative was published May 15, 2020 in the American Journal of Obstetrics & Gynecology.  A total of 46 pregnant patients within 6 large hospital systems (16 hospitals) were identified; these sites capture 40% of birth in the state.

 

From this data, we found:

--1 in 7 women required hospitalization for respiratory concerns

--1 in 8 had severe COVID-19 disease

--1 in 4 women had the timing of their delivery influenced by the COVID-19 diagnosis (out of 8 deliveries)

--Nearly all women with severe COVID-19 disease were either overweight or obese prior to pregnancy and many had other underlying conditions (asthma, hypertension).

 

This data begins to suggest that some women are at higher risk for severe COVID-19 disease and should take extra precautions.  This data echoes a recent case series published on a pre-print server from the UK also suggesting obesity and the 2nd/3rd trimester infections were associated with a higher risk for severe disease.  A highly elevated D-dimer may occur in some cases and time will tell if women with COVID-19 are at higher risk for blood clots.

 

This was a large collaboration led by UW – and with thanks to our UW team and community collaborators.

Contributors from our department included:

Erica M. LOKKEN, PhD, MS, Departments of Global Health and Obstetrics & Gynecology, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Shani DELANEY, MD, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Alisa KACHIKIS, MD, MS, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Nicole M. KRETZER, MD, PhD, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Anne ERICKSON, MD, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Joseph K. HWANG, MD, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Stephen A. MCCARTNEY, MD, PhD, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Kimberly K. MA, MD, Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington

Kristina ADAMS WALDORF, MD, Departments of Obstetrics & Gynecology and Global 55 Health, University of Washington, Seattle, Washington